Hydrogen chloride-ethyl acetate → HCID 73472956, compound

Participants

Reaction Steps

To a methanol solution of 1.73 g (4.5 mmol) of 5-hexylidene-3-[4-(imidazo[1,2-a]pyridin-8-yloxy)butyl]thiazolidine-2,4-dione, 1 ml of 4N hydrochloric acid-ethyl acetate was added, followed by stirring. After the solvent was distilled off, the residue was washed with ether to yield 1.73 g of an oily substance, which was then purified by recrystallization to yield 1.58 g (74%, white crystal) of the desired product.

Provenance & Evidence