反应详情

Treat the product of Step 1 (21.25 g, 91.96 mmoles) at room temperature with 130 ml. of HOAc saturated with HBr gas. Stir at room temperature for 2 days, then pour into 800 ml. of ice-water with stirring. Store the resultant gum in a freezer for two days, then decant the liquid from the solidified gum. Triturate the solid, filter, wash with water and air dry. Yield: 26.2 g (m.p.=80°-81° C.).

1. additionpour into 800 ml
2. waitStore the resultant gum in a freezer for two days
3. customdecant the liquid from the solidified gum
4. customTriturate the solid
5. filtrationfilter
6. washwash with water and air
7. customdry