反应详情

Dissolve the product of Step 2 (8.1 g, 25.96 mmoles) in 20 ml. of dry CH2Cl2. Add oxalyl chloride (8.1 g, 62.3 mmoles), followed by 50 μl of dry DMF and heat the solution to reflux for 3 h. Cool the solution to room temperature and remove the solvent and excess reagent using reduced pressure. Yield: 8.2 g (IR: 1785 cm-1).

1. temperatureheat the solution
2. temperatureto reflux for 3 h
3. customremove the solvent and excess reagent