Hydrogen Sulfide → 5-Thiocarbamoyl-1-tetralone

HRID 357625Notes

Reaction equation

HRID 357625 reaction equation
[C:1]([C:3]1[CH:12]=[CH:11][CH:10]=[C:9]2[C:4]=1[CH2:5][CH2:6][CH2:7][C:8]2=[O:13])#[N:2].[SH2:14]>N1C=CC=CC=1.C(N(CC)CC)C>[C:1]([C:3]1[CH:12]=[CH:11][CH:10]=[C:9]2[C:4]=1[CH2:5][CH2:6][CH2:7][C:8]2=[O:13])(=[S:14])[NH2:2]

Participants

5

Reactant 2

HCID 402Hydrogen SulfideHCID 109318735-Oxo-5,6,7,8-tetrahydronaphthalene-1-carbonitrile

Product 1

HCID 189379235-Thiocarbamoyl-1-tetralone

Reagents, catalysts & solvents 2

HCID 1049PyridineSolventHCID 8471TriethylamineSolvent

Procedure

Analogously to Example 29a), 10.6 g (62 mmol) of 5-cyano-l-tetralone in 200 ml of pyridine and 8.6 ml of triethylamine are treated with hydrogen sulfide and worked up. There is thus obtained the title compound in the form of yellow crystals, m.p. 200°-205°.

Sources & evidence

ORD record
ord-76404ce0fd9e42018ba5f0f8255456e6
Source dataset
uspto-grants-1998_11
Patent number
US05840911

Reaction notes

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