Sodium Hydroxide → HCID 18937673, compound

Participants

Reaction Steps

In the same manner as above, a solution of ethyl 1-(4-methoxybenzyl)-5-(4,5-dimethyl-2-nitrobenzoyl)-1,2,3-triazole-4-carboxylate (b-2) (2.48 g, 5.66 mmole) in tetrahydrofuran (30 ml) was hydrolyzed with a 1N aqueous sodium hydroxide solution (11.3 ml) at room temperature for 3 hours to give 1-(4-methoxybenzyl)-5-(4,5-dimethyl-2-nitrobenzoyl)-1,2,3-triazole-4-carboxylic acid (c-2': MP) as a crude product of brownish oil (2.448 g).

Provenance & Evidence