N-bromobutanimide → 3-bromo-5,6-dihydro-4-hydroxy-6,6-diphenyl-2H-pyran-2-one

HRID 357842Notes

Reaction equation

HRID 357842 reaction equation
[OH:1][C:2]1[CH2:7][C:6]([C:14]2[CH:19]=[CH:18][CH:17]=[CH:16][CH:15]=2)([C:8]2[CH:13]=[CH:12][CH:11]=[CH:10][CH:9]=2)[O:5][C:4](=[O:20])[CH:3]=1.C1C(=O)N([Br:28])C(=O)C1>>[Br:28][C:3]1[C:4](=[O:20])[O:5][C:6]([C:8]2[CH:13]=[CH:12][CH:11]=[CH:10][CH:9]=2)([C:14]2[CH:19]=[CH:18][CH:17]=[CH:16][CH:15]=2)[CH2:7][C:2]=1[OH:1]

Participants

3

Reactant 2

HCID 67184N-bromobutanimideHCID 546804105,6-dihydro-4-hydroxy-6,6-diphenyl-2H-pyran-2-one

Product 1

HCID 547215603-bromo-5,6-dihydro-4-hydroxy-6,6-diphenyl-2H-pyran-2-one

Procedure

The title compound was prepared as described in General Method 3 using 4.0 mmol of 5,6-dihydro-4-hydroxy-6,6-diphenyl-2H-pyran-2-one (prepared in Example W) and 4.0 mmol of NBS. The product was obtained as a solid. 1H NMR (DMSO-d6) δ 3.68 (s, 2 H), 7.27-7.40 (m, 10 H).

Workup

  1. customThe product was obtained as a solid

Sources & evidence

ORD record
ord-6dfbbf2e14f74f46b6a3a57bd5978f98
Source dataset
uspto-grants-1998_11
Patent number
US05840751

Reaction notes

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