反应详情

Into a beaker, are added, with stirring, 11.4 g (0.06 mole) of triisopropanolamine in 100 ml of isopropanol. The reaction medium is stirred and cooled to between 5° and 10° C. 19.2 g (0.06 mole) of 5-n-dodecanoylsalicylic acid are then added. The mixture is stirred for 30 min at room temperature and then the clear mixture is filtered. The filtrate is evaporated to dryness. An oil is obtained which crystallizes at room temperature. It is filtered on sintered glass. The white powder obtained is dried under vacuum over phosphoric anhydride. 29.1 g of product are obtained, equivalent to a yield of 95%.

1. additionInto a beaker, are added
2. stirringThe reaction medium is stirred
3. temperaturecooled to between 5° and 10° C
4. stirringThe mixture is stirred for 30 min at room temperature
5. filtrationthe clear mixture is filtered
6. customThe filtrate is evaporated to dryness
7. customAn oil is obtained which
8. customcrystallizes at room temperature
9. filtrationIt is filtered on sintered glass
10. customThe white powder obtained
11. dry with materialis dried under vacuum over phosphoric anhydride