HuagongsheHuagongshe Chemistry Print Report · For research reference only
Water → HCID 19037728, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Water | HCID 962 | — |
| Reactant | HCID 73509636 | HCID 73509636 | — |
| Product | HCID 19037728 | HCID 19037728 | — |
Reaction Steps
26 g of 4-(2-fluorophenyl)-1-tetralone oxime are added to 130 g of polyphosphoric acid pre-heated to 125°. The solution obtained is stirred at 125° for 30 minutes, cooled, mixed with ice and water and extracted with chloroform. After evaporation of the organic phase, the residue is crystallized from ethanol. There is obtained 5-(2-fluorophenyl)-1,3,4,5-tetrahydro-2H-1-benzazepin-2-one of melting point 210°-212°.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04464300 |
| Source dataset | uspto-grants-1984_08 |
| ORD ID | ord-12478248b1f147fa87fc962e1667ba2f |
| Source note | uspto-grants-1984_08 |