Hydrazine hydrate (1:1) → HCID 20449960, compound

Participants

Reaction Steps

A solution of 17.5 ml of hydrazine hydrate in 1.75 l of tetrahydrofuran is treated with 22 g of 7-chloro-5-(2-fluorophenyl)-1,3,4,5-tetrahydro-2H-1-benzazepine-2-thione. The solution is stirred under a stream of argon for 2 hours and then evaporated at 40° in vacuo. The residue is crystallized from ether and there is obtained 7-chloro-5-(2-fluorophenyl)-2-hydrazino-4,5-dihydro-2H-1-benzazepine of melting point 213°-215°.

Provenance & Evidence