反应详情

温度

60 °C

To 200 ml of acetone were added 10.0 g of L-sorbose and 57 mg of diphosphorus tetraiodide and the mixture was refluxed with stirring in a water bath at 60° C. for 4 hours. During this reaction, the refluxing solvent was dried with 20 g of Molecular Sieves 3A interposed between the reaction vessel and the cooling jacket. The reaction mixture was then subjected to an after-treatment similar to that described in Example 11 to give 8.60 g (59.5%) of 2,3:4,6-di-O-isopropylidene-L-sorbofuranose (purity ≥90%).

1. temperaturethe mixture was refluxed
2. customDuring this reaction
3. dry with materialthe refluxing solvent was dried with 20 g of Molecular Sieves 3A