Methyl[1-(2-methylphenyl)ethyl]amine → HCID 15589250, compound

HRID 358180Notes

Reaction equation

HRID 358180 reaction equation
[CH2:1]([C:3]([N:12]=[C:13]=[O:14])([CH2:10][CH3:11])[C:4]1[CH:9]=[CH:8][CH:7]=[CH:6][CH:5]=1)[CH3:2].[CH3:15][C:16]1[CH:25]=[CH:24][CH:23]=[CH:22][C:17]=1[CH:18]([NH:20][CH3:21])[CH3:19]>>[CH3:15][C:16]1[CH:25]=[CH:24][CH:23]=[CH:22][C:17]=1[CH:18]([N:20]([CH3:21])[C:13]([NH:12][C:3]([CH2:10][CH3:11])([CH2:1][CH3:2])[C:4]1[CH:5]=[CH:6][CH:7]=[CH:8][CH:9]=1)=[O:14])[CH3:19]

Participants

3

Reactant 2

HCID 16771015Methyl[1-(2-methylphenyl)ethyl]amineHCID 20449307HCID 20449307, compound

Product 1

HCID 15589250HCID 15589250, compoundYield 93.6%

Procedure

A mixture consisting of 9.5 g of α,α-diethylbenzylisocyanate and 7.5 g of N-(2-methyl-α-methylbenzyl)-N-methylamine was allowed to stand for 3 hours at room temperature. The white deposit formed was then filtered off. Washing with n-hexane and recrystallization from ethanol gave 15.9 g of the product, mp 93.0°-94.0° C.

Workup

  1. customThe white deposit formed
  2. filtrationwas then filtered off
  3. washWashing with n-hexane and recrystallization from ethanol

Sources & evidence

ORD record
ord-4f534a0195fa4771a28d11d2e4b84d17
Source dataset
uspto-grants-1984_08
Patent number
US04465509

Reaction notes

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