Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Triethylamine | HCID 8471 | — |
| Reactant | Acetoxyacetyl chloride | HCID 26297 | — |
| Reactant | 2,2,2-trifluoro-N-methylethanamine | HCID 520301 | — |
| Solvent | Toluene | HCID 1140 | — |
| Product | HCID 13090849 | HCID 13090849 | 79.8% |
Reaction Steps
10 g (0.1 mol) of triethylamine and 13.6 g (0.1 mol) of acetoxyacetyl chloride were added to a solution of 9.9 g (0.1 mol) of N-(2,2,2-trifluoroethyl)-N-methylamine in 150 ml of toluene and the mixture was stirred at 20° C. for 15 hours. It was then filtered and the filtrate was distilled. 17 g (79.8% of theory) of N-(2,2,2-trifluoroethyl)-N-methyl-acetoxyacetamide of boiling point 110° C./3 mbar were obtained. ##STR11## was obtained analogously; ND20 :1.4333. ##STR12##
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| Patent number | US04465504 |
|---|
| Source dataset | uspto-grants-1984_08 |
|---|
| ORD ID | ord-15424f31f2724765b605ee0a38e34833 |
|---|
| Source note | uspto-grants-1984_08 |
|---|
