((2-n-butyl-6,7-dichloro-2-cyclopentyl-2,3-dihydro-1-oxo-1H-inden-5-yl)oxy)acetic acid, (+)- → 2-Butyl-6,7-dichloro-2-cyclopentyl-5-hydroxy-1-indanone

Participants

Reaction Steps

By following substantially the procedure in Example 8, Step A, but substituting for (+) 6,7-dichloro-2-cyclopentyl-2,3-dihydro-2-methyl-1-oxo-1H-inden-5-yl)oxy]acetic acid an equimolar quantity of (-) [(2-butyl-6,7-dichloro-2-cyclopentyl-2,3-dihydro-1-oxo-1H-inden-5-yl)oxy]acetic acid, there is obtained (-) 2-butyl-6,7-dichloro-2-cyclopentyl-2,3-dihydro-5-hydroxy-1H-inden-1-one which is used in Step C without further purification.

Provenance & Evidence