Benzene → Nitrobenzene
Reaction equation
FC(F)(F)C(O)=O.[N+:8]([O-:11])([O-])=[O:9].[Na+].[CH:13]1[CH:18]=[CH:17][CH:16]=[CH:15][CH:14]=1>>[N+:8]([C:13]1[CH:18]=[CH:17][CH:16]=[CH:15][CH:14]=1)([O-:11])=[O:9]Participants
4
Procedure
A. Spitzer and R. Stewart, J. Org. Chem., 1974, 39, 3936 disclose nitrating aromatics in the presence of a trifluoroacetic acid medium. In one example benzene and sodium nitrate were reacted together in a 1:1 molar ratio at room temperature to form nitrobenzene in a 99.9% yield. In another example sodium nitrite was reacted with benzene in the same 1:1 molar concentration and at the same temperature as the nitrate example, however, nitrobenzene yield was only about 3%.
Sources & evidence
- ORD record
- ord-2fbeed0e6ad94a01a389adc4a549e195
- Source dataset
- uspto-grants-1984_08
- Patent number
- US04465876
Reaction notes
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