HuagongsheHuagongshe Chemistry Print Report · For research reference only
3-Amino-4-methoxycyclobut-3-ene-1,2-dione → 1-[3-[4-(Piperidinomethyl)pyrid-2-yloxy]prop-1-ylamino]-2-aminocyclobut-1-ene-3,4-dione
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 3-Amino-4-methoxycyclobut-3-ene-1,2-dione | HCID 13452205 | — |
| Reactant | 3-({4-[(Piperidin-1-yl)methyl]pyridin-2-yl}oxy)propan-1-amine | HCID 14625102 | — |
| Solvent | Pyridine | HCID 1049 | — |
| Product | 1-[3-[4-(Piperidinomethyl)pyrid-2-yloxy]prop-1-ylamino]-2-aminocyclobut-1-ene-3,4-dione | HCID 20448694 | — |
Reaction Steps
1-Amino-2-methoxy-cyclobut-1-ene-3,4-dione is mixed with 3-[4-(piperidinomethyl)pyrid-2-yloxy]prop-1-ylamine in anhydrous pyridine and is heated at reflux temperature to give the title product.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04466970 |
| Source dataset | uspto-grants-1984_08 |
| ORD ID | ord-e1531e787e9b43b0a36bbccd9a32a89d |
| Source note | uspto-grants-1984_08 |