Diazomethane → HCID 13448671, compound

HRID 358356Notes

Reaction equation

HRID 358356 reaction equation
[C:1]([OH:8])(=[O:7])[CH2:2][C:3]#[C:4][CH2:5][CH3:6].[N+](=[CH2:11])=[N-]>CCOCC.C(O)(=O)C>[CH3:11][O:7][C:1](=[O:8])[CH2:2][C:3]#[C:4][CH2:5][CH3:6]

Participants

5

Reactant 2

HCID 9550DiazomethaneHCID 53126353-Hexynoic acid

Product 1

HCID 13448671HCID 13448671, compound

Reagents, catalysts & solvents 2

HCID 176Acetic AcidCatalystHCID 3283Diethyl EtherSolvent

Procedure

A solution of 5.9 g of 3-hexynoic acid in 50 ml of ether is treated with a slight excess of ethereal diazomethane solution. A few drops of glacial acetic acid are added to the mixture, the mixture is concentrated in vacuo and then distilled. 5.65 g of the title compound are obtained: b.p. 62° C. (5 mm).

Workup

  1. concentrationthe mixture is concentrated in vacuo
  2. distillationdistilled

Sources & evidence

ORD record
ord-f9726011908648edaaa2665197868482
Source dataset
uspto-grants-1984_08
Patent number
US04466969

Reaction notes

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