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HRID358376

反应详情

EQUATION

反应方程式

HRID 358376 的结构方程式

REACTANTS

反应物

3
结构：c1ccncc1
HCID1049

Pyridine

C5H5N

结构：CC(=O)OC(C)=O
HCID7918

Acetic anhydride

C4H6O3

结构：CC(C)(C)[Si](C)(C)OC1C=C(SCCCCCCO)C(=O)C1
HCID20448815

未命名化合物

PRODUCTS

生成物

1
结构：CC(=O)OCCCCCCSC1=CC(O[Si](C)(C)C(C)(C)C)CC1=O
HCID20448814

未命名化合物

收率 96.5%

AUXILIARIES

试剂、催化剂与溶剂

1
结构：CO
溶剂HCID887

Methanol

CH4O

PROCEDURE

实验过程

700 mg (2.13 mmoles) of 4(RS)-t-butyldimethylsilyloxy-2-(6-hydroxyhexylthio)-2-cyclopentenone, 1020 mg (10 mmoles) of acetic anhydride and 1580 mg (20 mmoles) of pyridine were mixed, and stirred at room temperature for 2 hours. After the reaction, methanol was added. The solvent was removed to give 795 mg of 4-t-butyldimethylsilyloxy-2-(6-acetoxyhexylthio)-2-cyclopentenone as a nearly pure product.

WORKUP

后处理

  1. additionwas added
  2. customThe solvent was removed