HuagongsheHuagongshe Chemistry Print Report · For research reference only
Ethyl isobutyrate → HCID 20066956, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Ethyl isobutyrate | HCID 7342 | — |
| Reactant | 1,8-Dibromooctane | HCID 78310 | — |
| Reactant | Lithium diisopropylamide | HCID 2724682 | — |
| Solvent | Hexamethylphosphoramide | HCID 12679 | — |
| Product | HCID 20066956 | HCID 20066956 | 16.5% |
Reaction Steps
Using the method described in Example 5(i), 1,8-dibromooctane (27.2 g, 0.1 mol) and ethylisobutyrate (10.44 g, 0.09 mol) were reacted in the presence of lithium diisopropylamide (67 ml, 0.1 mol) and hexamethylphosphoramide (22 g) to give the title compound (4.56 g) as an oil.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04997847 |
| Source dataset | uspto-grants-1991_03 |
| ORD ID | ord-1e8a137e661d40199c3c8e749e81cd5f |
| Source note | uspto-grants-1991_03 |