Potassium Carbonate → HCID 20066949, compound

HRID 358627Notes

Reaction equation

HRID 358627 reaction equation
[CH3:1][C:2]([CH3:17])([CH2:8][CH2:9][CH2:10][CH2:11][CH2:12][CH2:13][CH2:14][CH2:15]Br)[C:3]([O:5][CH2:6][CH3:7])=[O:4].[Cl:18][C:19]1[CH:24]=[CH:23][C:22]([S:25]([NH2:28])(=[O:27])=[O:26])=[CH:21][CH:20]=1.C(=O)([O-])[O-].[K+].[K+]>>[CH2:6]([O:5][C:3](=[O:4])[C:2]([CH3:17])([CH3:1])[CH2:8][CH2:9][CH2:10][CH2:11][CH2:12][CH2:13][CH2:14][CH2:15][NH:28][S:25]([C:22]1[CH:21]=[CH:20][C:19]([Cl:18])=[CH:24][CH:23]=1)(=[O:27])=[O:26])[CH3:7]

Participants

4

Reactant 3

HCID 11430Potassium CarbonateHCID 668244-ChlorobenzenesulfonamideHCID 20066956HCID 20066956, compound

Product 1

HCID 20066949HCID 20066949, compoundYield 47.8%

Procedure

Ethyl 2,2-dimethyl-10-bromodecanoate (2.2 g, 0.007 mol) was treated with 4-chlorobenzenesulphonamide (2.6 g, 0.014 mol) and potassium carbonate by the method described in Example 5(ii) to give title compound (1.4 g) as an oil.

Sources & evidence

ORD record
ord-73f5bb1d8ec642d3be9aaa319a3a5748
Source dataset
uspto-grants-1991_03
Patent number
US04997847

Reaction notes

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