4-Chlorobenzenesulfonyl chloride → 11-(4-Chlorobenzenesulphonamido)undecanoic Acid

HRID 358636Notes

Reaction equation

HRID 358636 reaction equation
[NH2:1][CH2:2][CH2:3][CH2:4][CH2:5][CH2:6][CH2:7][CH2:8][CH2:9][CH2:10][CH2:11][C:12]([OH:14])=[O:13].[Cl:15][C:16]1[CH:21]=[CH:20][C:19]([S:22](Cl)(=[O:24])=[O:23])=[CH:18][CH:17]=1>>[Cl:15][C:16]1[CH:21]=[CH:20][C:19]([S:22]([NH:1][CH2:2][CH2:3][CH2:4][CH2:5][CH2:6][CH2:7][CH2:8][CH2:9][CH2:10][CH2:11][C:12]([OH:14])=[O:13])(=[O:24])=[O:23])=[CH:18][CH:17]=1

Participants

3

Reactant 2

HCID 73984-Chlorobenzenesulfonyl chlorideHCID 1708311-Aminoundecanoic acid

Product 1

HCID 1319213811-(4-Chlorobenzenesulphonamido)undecanoic Acid

Procedure

11-Aminoundecanoic acid (4.02 g, 0.02 mol) was treated with 4-chlorobenzenesulphonyl chloride (4.22 g, 0.02 mol) as described in Example 4 to give the title compound which was recrystallised from 2-propanol/ether (1.8 g, m.p. 128°-9° C.).

Sources & evidence

ORD record
ord-2f0ef4b2716e48929b1b45aec994ea09
Source dataset
uspto-grants-1991_03
Patent number
US04997847

Reaction notes

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