2-Ethylhexanoyl chloride → HCID 20066911, compound

Participants

Reaction Steps

Using an analogous procedure to that described in Example 1, but starting from methyl 4-(6-aminoindazol-1-ylmethyl)-3-methoxybenzoate and 2-ethylhexanoyl chloride, there was obtained methyl 4-[6-(2-ethylhexanamido)indazol-1-ylmethyl]-3-methoxybenzoate in 68% yield as a white solid, m.p. 135.5°-136.5° C.; microanalysis, found: C, 68.37; H, 7.10; N, 9.43%; C25H31,N3O4 requires: C, 68.64; H, 7.14; N, 9.60%.

Provenance & Evidence