Ethyl bromoacetate → HCID 14536939, compound

Participants

Reaction Steps

1.06 g of sodium carbonate or 3.26 g of cesium carbonate were added to a stirred solution of 2.47 g of 4-(1-oxo-2-trifluoroacetamidoethyl)-phenol (1e) in 5 ml of dimethyl sulfoxide at room temperature and, after 30 minutes, 1.83 g of ethyl bromoacetate were introduced. Precipitating crystalline solid gradually made the mixture more viscous. After about 2 hours, the mixture solidified to a thick, unstirrable crystal slurry.

Provenance & Evidence