HCID 20065707, compound → HCID 20065692, compound

HRID 358964Notes

Reaction equation

HRID 358964 reaction equation
[N:1]1([C:7]([CH:9]2[C:14]3[CH:15]=[CH:16][S:17][C:13]=3[CH2:12][CH2:11][NH:10]2)=O)[CH2:6][CH2:5][CH2:4][CH2:3][CH2:2]1.[H-].[Al+3].[Li+].[H-].[H-].[H-]>C1COCC1>[N:1]1([CH2:7][CH:9]2[C:14]3[CH:15]=[CH:16][S:17][C:13]=3[CH2:12][CH2:11][NH:10]2)[CH2:6][CH2:5][CH2:4][CH2:3][CH2:2]1

Participants

4

Reactant 2

HCID 20065707HCID 20065707, compoundHCID 21226445Aluminium lithium hydride

Product 1

HCID 20065692HCID 20065692, compound

Reagents, catalysts & solvents 1

HCID 8028TetrahydrofuranSolvent

Procedure

Prepared as Description No. 4, from 1.7 g (6.8 mmoles) of 4-(piperidin-1-yl)carbonyl-4,5,6,7-tetrahydrothieno[3,2-c]pyridine and 600 mg (15.79 mmoles) of lithium aluminium hydride in 50 ml of dry THF.

Workup

  1. customPrepared as Description No

Sources & evidence

ORD record
ord-f63adfa9e53c40b189810bceb6c9bd4b
Source dataset
uspto-grants-1991_03
Patent number
US04999359

Reaction notes

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