Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Hydrochloric Acid | HCID 313 | — |
| Reactant | Potassium Hydroxide | HCID 14797 | — |
| Reactant | Potassium | HCID 5462222 | — |
| Reactant | Glyoxylic acid, monohydrate | HCID 15620607 | — |
| Reactant | HCID 178478691 | HCID 178478691 | — |
| Solvent | Water | HCID 962 | — |
| Product | 126167-33-7 | HCID 67945944 | — |
Reaction Steps
25.00 g (0.135 moles) of histamine dihydrochloride were dissolved in 125 ml of water; 26.92 g (0.40 moles) of 85% potassium hydroxide were then added to the cooled solution. A solution of 12.51 g (0.136 moles) of monohydrate glyoxylic acid and 9.00 g (0.136 moles) of 85% potassium hydroxyde in 125 ml of water was dropped into the first one and the reaction mixture heated at 90° C., 6 hours, cooled, treated with conc. HCl and concentrated in vacuo to dryness.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| Patent number | US04999359 |
|---|
| Source dataset | uspto-grants-1991_03 |
|---|
| ORD ID | ord-0a44ffc5edc54a61b6d82e57a8b23284 |
|---|
| Source note | uspto-grants-1991_03 |
|---|
