反应详情

This compound was synthesized by the condensation of triphenylmethanol (2.84 g, 10.8 mmoles) with mercaptoacetic acid (0.75 ml, 10.8 mmoles) in 19 ml trifluoracetic acid. The TFA was removed in vacuo, giving an orange oil, which was purified by dissolution in ether and extraction with 1 N NaOH. The aqueous phase was acidified with 6N HCl, and extracted with two 30 ml portions of ether. The ethereal phase was dried over MgSO4 and evaporated to give 3.41 g (93%) of a white solid.

1. customThe TFA was removed in vacuo
2. customgiving an orange oil, which
3. customwas purified by dissolution in ether
4. extractionextraction with 1 N NaOH
5. extractionextracted with two 30 ml portions of ether
6. dry with materialThe ethereal phase was dried over MgSO4
7. customevaporated