Dimethyl Sulfate → HCID 15170292, compound

HRID 359250Notes

Reaction equation

HRID 359250 reaction equation
S(OC)(O[CH3:5])(=O)=O.[CH:8]1[C:16]2[NH:15][C:14]3[C:17]4[CH:23]=[CH:22][CH:21]=[CH:20][C:18]=4[S:19][C:13]=3[C:12]=2[CH:11]=[CH:10][CH:9]=1>C(Cl)Cl.CCCCCC>[CH3:5][N:15]1[C:16]2[CH:8]=[CH:9][CH:10]=[CH:11][C:12]=2[C:13]2[S:19][C:18]3[CH:20]=[CH:21][CH:22]=[CH:23][C:17]=3[C:14]1=2

Participants

4

Reactant 2

HCID 6497Dimethyl SulfateHCID 35426110H-[1]Benzothieno[3,2-b]indole

Product 1

HCID 15170292HCID 15170292, compoundYield 91.9%

Reagents, catalysts & solvents 1

HCID 21226440Methylenechloride HexaneSolvent

Procedure

Using the procedure outlined in Example 34A except that dimethyl sulfate was used as the alkylating agent, 10H-[1]benzothieno[3,2-b]indole (prepared by the method of K. E. Chippendale and B. Iddon, JCS Perkin Trans. I, 2023 (1972)) gave a 91.9% yield of 10-methyl-10H-[1]benzothieno[3,2-b]indole, mp 175°-176°, (CH2Cl2 /hexane), (C,H,N,S).

Workup

  1. customprepared by the method of K

Sources & evidence

ORD record
ord-4be274b2a3404dd9870b94ec7e1adef5
Source dataset
uspto-grants-1991_03
Patent number
US04999369

Reaction notes

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