Acetic Acid → Acetaldehyde, 2-[4-(1,1-dimethylethyl)phenoxy]-

HRID 35932Notes

Reaction equation

HRID 35932 reaction equation
[CH3:1][C:2]([C:5]1[CH:17]=[CH:16][C:8]([O:9][CH2:10][CH:11](OC)[O:12]C)=[CH:7][CH:6]=1)([CH3:4])[CH3:3].C(O)(=O)C.Cl>O>[CH3:4][C:2]([C:5]1[CH:6]=[CH:7][C:8]([O:9][CH2:10][CH:11]=[O:12])=[CH:16][CH:17]=1)([CH3:1])[CH3:3]

Participants

5

Reactant 3

HCID 176Acetic AcidHCID 313Hydrochloric AcidHCID 3085718Benzene, 1-(2,2-dimethoxyethoxy)-4-(1,1-dimethylethyl)-

Product 1

HCID 166373Acetaldehyde, 2-[4-(1,1-dimethylethyl)phenoxy]-

Reagents, catalysts & solvents 1

HCID 962WaterSolvent

Procedure

To a mixture of 5.00 g (0.021 mol.) of 2-[4-(1,1-dimethylethyl)phenoxy]-1,1-dimethoxyethane and 60 ml of acetic acid, there was added 6 ml of hydrochloric acid (36N) and the reaction mixture was stirred at room temperature for one hour. Then the reaction mixture was poured into 300 ml of cold water and filtrated quickly to recover a resultant white precipitate. The precipitate was obtained as a wet cake of 2-[4-(1,1-dimethylethyl) phenoxy]acetoaldehyde without being dried too much and was quickly used in the next step of the production procedure.

Workup

  1. filtrationfiltrated quickly
  2. customto recover a resultant white precipitate

Sources & evidence

ORD record
ord-6956db1953e8473ea056e7c24c0a9a75
Source dataset
uspto-grants-1995_05
Patent number
US05411979

Reaction notes

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