Methyl 1-(2-phenylethyl)-1,4,5,6-tetrahydro-3-pyridyl ketone → Propyl 1-propyl-1,4,5,6-tetrahydro-3-pyridyl ketone

HRID 359324Notes

Reaction equation

HRID 359324 reaction equation
[Br-].[CH2:2]([N+:5]1[CH:10]=[CH:9][CH:8]=[C:7]([C:11](=[O:15])[CH2:12][CH2:13][CH3:14])[CH:6]=1)[CH:3]=[CH2:4].C1(CCN2CCCC(C(C)=O)=C2)C=CC=CC=1>>[CH2:2]([N:5]1[CH2:10][CH2:9][CH2:8][C:7]([C:11]([CH2:12][CH2:13][CH3:14])=[O:15])=[CH:6]1)[CH2:3][CH3:4]

Participants

3

Reactant 2

HCID 18963355Methyl 1-(2-phenylethyl)-1,4,5,6-tetrahydro-3-pyridyl ketoneHCID 189633651-(2-Propenyl)-3-butyryl pyridinium bromide

Product 1

HCID 18963391Propyl 1-propyl-1,4,5,6-tetrahydro-3-pyridyl ketone

Procedure

1-(2-Propenyl)-3-butyryl pyridinium bromide was hydrogenated according to the procedure described in Part (b) of Example 6 to give propyl 1-propyl-1,4,5,6-tetrahydro-3-pyridyl ketone. The product was distilled as a pale yellow oil (b.pt 150-153°C./0.3 mm Hg)

Sources & evidence

ORD record
ord-e3f19aebb1074bc7ac4c7ff0c47d1fae
Source dataset
uspto-grants-1991_03
Patent number
US05000946

Reaction notes

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