1-Bromopropane → HCID 54133669, compound

HRID 359332Notes

Reaction equation

HRID 359332 reaction equation
[CH3:1][C:2]1([CH3:13])[CH2:11][C:10]2[NH:9][CH2:8][CH2:7][CH2:6][C:5]=2[C:4](=[O:12])[CH2:3]1.Br[CH2:15][CH2:16][CH3:17].CC(N1CCCC(C(C)=O)=C1)C>>[CH3:1][C:2]1([CH3:13])[CH2:11][C:10]2[N:9]([CH2:15][CH2:16][CH3:17])[CH2:8][CH2:7][CH2:6][C:5]=2[C:4](=[O:12])[CH2:3]1

Participants

4

Reactant 3

HCID 78401-BromopropaneHCID 118196217,7-Dimethyl-2,3,4,6,7,8-hexahydroquinolin-5(1H)-oneHCID 18963350HCID 18963350, compound

Product 1

HCID 54133669HCID 54133669, compound

Procedure

7,7-Dimethyl-1,2,3,4,7,8-hexahydro-quinolin-5 (6H)-one [prepared by the method of Grob and Kiefer, Helv. Chim Acta., 48 799, (1964)]was reacted with 1-bromopropane according to the procedure of Part (b) of Example 1 to give 7,7-dimethyl-1,2,3,4,7, 8-hexahydro-1-propyl-quinolin-5(6H)-one (17) as an oil.

Sources & evidence

ORD record
ord-2372855a6d184dc099b9a007cb3ac4a6
Source dataset
uspto-grants-1991_03
Patent number
US05000946

Reaction notes

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