Anthranilamide → HCID 797250, compound

HRID 359537Notes

Reaction equation

HRID 359537 reaction equation
[NH2:1][C:2]1[CH:10]=[CH:9][CH:8]=[CH:7][C:3]=1[C:4]([NH2:6])=[O:5].[CH3:11][C:12]1[CH:22]=[CH:21][CH:20]=[CH:19][C:13]=1[C:14]([N:16]=[C:17]=[S:18])=[O:15]>CCOCC>[NH2:6][C:4]([C:3]1[CH:7]=[CH:8][CH:9]=[CH:10][C:2]=1[NH:1][C:17](=[S:18])[NH:16][C:14](=[O:15])[C:13]1[CH:19]=[CH:20][CH:21]=[CH:22][C:12]=1[CH3:11])=[O:5]

Participants

4

Reactant 2

HCID 6942AnthranilamideHCID 1413962-Methylbenzoyl isothiocyanate

Product 1

HCID 797250HCID 797250, compoundYield 95.8%

Reagents, catalysts & solvents 1

HCID 3283Diethyl EtherSolvent2×

Procedure

To a stirred mixture of 4.9 g of 2-aminobenzamide and 200 ml of ether was added dropwise, a solution of 6.67 g of 2-methylbenzoyl isothiocyanate in 100 ml of ether over 15 minutes After a few hours, the solid was collected, giving 10.8 g of the desired product as grey crystals, mp 181°-185° C. (dec.).

Workup

  1. additionwas added dropwise
  2. customthe solid was collected

Sources & evidence

ORD record
ord-4b38721960304ccfa0f1595365e708ac
Source dataset
uspto-grants-1991_03
Patent number
US05001157

Reaction notes

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