n-Octanoyl-5-salicylic acid → HCID 178442659, compound

HRID 359552Notes

Reaction equation

HRID 359552 reaction equation
[C:1]([C:10]1[CH:18]=[C:14]([C:15]([OH:17])=[O:16])[C:13]([OH:19])=[CH:12][CH:11]=1)(=[O:9])[CH2:2][CH2:3][CH2:4][CH2:5][CH2:6][CH2:7][CH3:8].[CH3:20][C:21]([CH2:24][C:25]([C:28]1[CH:29]=[CH:30][C:31]([O:34][CH2:35][CH2:36][O:37][CH2:38][CH2:39][N+:40]([CH2:43][C:44]2[CH:45]=[CH:46][CH:47]=[CH:48][CH:49]=2)([CH3:42])[CH3:41])=[CH:32][CH:33]=1)([CH3:27])[CH3:26])([CH3:23])[CH3:22].C(=O)([O-])[O-]>CO>[CH3:23][C:21]([CH2:24][C:25]([C:28]1[CH:29]=[CH:30][C:31]([O:34][CH2:35][CH2:36][O:37][CH2:38][CH2:39][N+:40]([CH2:43][C:44]2[CH:45]=[CH:46][CH:47]=[CH:48][CH:49]=2)([CH3:41])[CH3:42])=[CH:32][CH:33]=1)([CH3:26])[CH3:27])([CH3:20])[CH3:22].[C:1]([C:10]1[CH:18]=[C:14]([C:15]([O-:17])=[O:16])[C:13]([OH:19])=[CH:12][CH:11]=1)(=[O:9])[CH2:2][CH2:3][CH2:4][CH2:5][CH2:6][CH2:7][CH3:8]

Participants

4

Reactant 2

HCID 9838158n-Octanoyl-5-salicylic acidHCID 86744670Benzethonium carbonate

Product 1

HCID 178442659HCID 178442659, compoundYield 193.7%

Reagents, catalysts & solvents 1

HCID 887MethanolSolvent2×

Procedure

2.2 g (8.4 mmol) of 5-octanoylsalicylic acid, dissolved beforehand in 100 ml of methanol, are added to a solution of 3.7 g (4.2 mmol) of benzethonium carbonate dissolved in 100 ml of methanol; the mixture is stirred for 1 hour at room temperature, the solution is then filtered and the filtrate is evaporated to dryness to give 5.5 g (98% yield) of benzethonium 5-octanoylsalicylate.

Workup

  1. filtrationthe solution is then filtered
  2. customthe filtrate is evaporated to dryness

Sources & evidence

ORD record
ord-bf8c077ac18f44feba68d84a5a06ceef
Source dataset
uspto-grants-1991_03
Patent number
US05001156

Reaction notes

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