5-Dodecanoylsalicylic acid → HCID 178442658, compound

HRID 359553Notes

Reaction equation

HRID 359553 reaction equation
[C:1]([C:14]1[CH:22]=[C:18]([C:19]([OH:21])=[O:20])[C:17]([OH:23])=[CH:16][CH:15]=1)(=[O:13])[CH2:2][CH2:3][CH2:4][CH2:5][CH2:6][CH2:7][CH2:8][CH2:9][CH2:10][CH2:11][CH3:12].[CH3:24][C:25]([CH2:28][C:29]([C:32]1[CH:33]=[CH:34][C:35]([O:38][CH2:39][CH2:40][O:41][CH2:42][CH2:43][N+:44]([CH2:47][C:48]2[CH:49]=[CH:50][CH:51]=[CH:52][CH:53]=2)([CH3:46])[CH3:45])=[CH:36][CH:37]=1)([CH3:31])[CH3:30])([CH3:27])[CH3:26].C(=O)([O-])[O-]>C(O)C.CO>[CH3:27][C:25]([CH2:28][C:29]([C:32]1[CH:33]=[CH:34][C:35]([O:38][CH2:39][CH2:40][O:41][CH2:42][CH2:43][N+:44]([CH2:47][C:48]2[CH:49]=[CH:50][CH:51]=[CH:52][CH:53]=2)([CH3:45])[CH3:46])=[CH:36][CH:37]=1)([CH3:30])[CH3:31])([CH3:24])[CH3:26].[C:1]([C:14]1[CH:22]=[C:18]([C:19]([O-:21])=[O:20])[C:17]([OH:23])=[CH:16][CH:15]=1)(=[O:13])[CH2:2][CH2:3][CH2:4][CH2:5][CH2:6][CH2:7][CH2:8][CH2:9][CH2:10][CH2:11][CH3:12]

Participants

5

Reactant 2

HCID 97971525-Dodecanoylsalicylic acidHCID 86744670HCID 86744670, compound

Product 1

HCID 178442658HCID 178442658, compoundYield 192.1%

Reagents, catalysts & solvents 2

HCID 702EthanolSolventHCID 887MethanolSolvent

Procedure

2 g (6.4 mmol) of 5-dodecanoylsalicylic acid, dissolved beforehand in 100 ml of ethanol, are added to a solution of 2.82 g (3.2 mmol) of benzethonium carbonate dissolved in 100 ml of methanol; the mixture is stirred for 1 hour at room temperature, the solution is then filtered and the filtrate is evaporated to dryness to give 4.5 g (97% yield) of benzethonium 5-dodecanoylsalicylate.

Workup

  1. filtrationthe solution is then filtered
  2. customthe filtrate is evaporated to dryness

Sources & evidence

ORD record
ord-d3d404f71b0c453ba69cdfb61ad0b972
Source dataset
uspto-grants-1991_03
Patent number
US05001156

Reaction notes

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