Isonicotinic Acid → Isonicotinic Acid

HRID 359654Notes

Reaction equation

HRID 359654 reaction equation
[C:1]([OH:9])(=[O:8])[C:2]1[CH:7]=[CH:6][N:5]=[CH:4][CH:3]=1>O>[C:1]([OH:9])(=[O:8])[C:2]1[CH:7]=[CH:6][N:5]=[CH:4][CH:3]=1.[N:5]1[CH:6]=[CH:7][C:2]([CH3:1])=[CH:3][CH:4]=1

Participants

4

Reactant 1

HCID 5922Isonicotinic Acid

Product 2

HCID 5922Isonicotinic AcidHCID 79634-Methylpyridine

Reagents, catalysts & solvents 1

HCID 962WaterSolvent2×

Procedure

Solubility of the isonicotinic acid in pure water was measured as less than 1 wt %. Impressively, isonicotinic acid formed a saturated solution at 21 wt% acid, 35 wt% water, and 39 wt% gamma-picoline.

Sources & evidence

ORD record
ord-08a5b573426b43c29a94bda69ac387f6
Source dataset
uspto-grants-1991_03
Patent number
US05002641

Reaction notes

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