反应详情

4.8 g (0.03 mol) trans-4-nitroxycyclohexylamine are mixed with 5.7 ml 4-butyrolactone and stirred for 3 d at room temperature. For the removal of the excess lactone, it is filtered over a silicic gel acid with ethyl acetate. After collection of the pure fractions, it is distilled in a vacuum, triturated with ether and filtered off with suction. There remain 2.1 g of the title compound of the melting point 58°-60° C., i.e. 28% of theory.

1. customFor the removal of the excess lactone, it
2. filtrationis filtered over a silicic gel acid with ethyl acetate
3. customAfter collection of the pure fractions, it
4. distillationis distilled in a vacuum
5. customtriturated with ether
6. filtrationfiltered off with suction