HuagongsheHuagongshe Chemistry Print Report · For research reference only
1,1'-Biphenyl, mixt. with 1,1'-oxybis(benzene) → 2-(4-Methoxyphenyl)-5-methyloxazole
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1,1'-Biphenyl, mixt. with 1,1'-oxybis(benzene) | HCID 24670 | — |
| Reactant | 4-(4,5-Dimethyl-2-oxazolyl)phenol | HCID 135621474 | — |
| Catalyst | Copper | HCID 23978 | — |
| Product | 2-(4-Methoxyphenyl)-5-methyloxazole | HCID 11644063 | 35.5% |
Reaction Steps
2-(4-Methoxyphenyl)-5-methyloxazole was prepared in 35.5% yield of decarboxylation of the compound of part (c) with copper powder in Dowtherm at reflux temperature. The isolated product was distilled, b.p. 136°-140° C. (0.1 mm).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05002960 |
| Source dataset | uspto-grants-1991_03 |
| ORD ID | ord-633c85ea63ef4eb3b73100e83b704d49 |
| Source note | uspto-grants-1991_03 |