HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-Chloroethyl chloroformate → 1-Chloroethyl N-[3-(10,11-dihydro-5H-dibenz[b,f]azepin-5-yl)]propyl-N-methylcarbamate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-Chloroethyl chloroformate | HCID 12305 | — |
| Reactant | Desipramine Hydrochloride | HCID 65327 | — |
| Product | 1-Chloroethyl N-[3-(10,11-dihydro-5H-dibenz[b,f]azepin-5-yl)]propyl-N-methylcarbamate | HCID 15679987 | 86% |
Reaction Steps
Following the general procedure of Example 50, but using 1.5 g (0.005 mol) of desipramine hydrochloride and 0.86 g (0.006 mol) chloroethyl chloroformate and carrying out the reaction at 5°-10° C. for 2 hours, gave 1.6 g (86%) of the title compound as a colorless oil.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05002935 |
| Source dataset | uspto-grants-1991_03 |
| ORD ID | ord-1f68f471672b475e971807d6b8252c2f |
| Source note | uspto-grants-1991_03 |