Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Tetrahydrofuran | HCID 8028 | — |
| Reactant | Iodide Ion | HCID 30165 | — |
| Reactant | N-(2-Chloroethyl)-N'-[2-(3-pyridinecarbonyloxy)ethyl]-N-nitrosourea | HCID 15680044 | — |
Reaction Steps
A solution of the product of Example 122 (1.5 g, 5 mmol) in 40 mL of tetrahydrofuran was treated with excess iodide. The mixture was stirred at 50° C. for 4 hours. The finely crystalline, yellow solid thus obtained (1.8 g, 82%) melted at 120°-121° C. and had the structure ##STR153## as confirmed by elemental analysis.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| Patent number | US05002935 |
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| Source dataset | uspto-grants-1991_03 |
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| ORD ID | ord-5375fcb3b4934380b1154b7b5222d081 |
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| Source note | uspto-grants-1991_03 |
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