Chlorotrimethylsilane → HCID 15667547, compound

HRID 359930Notes

Reaction equation

HRID 359930 reaction equation
[CH3:1][O:2][C:3]1[CH:4]=[C:5]([CH:8]=[C:9]([O:13][CH3:14])[C:10]=1[O:11][CH3:12])[CH:6]=[O:7].[C-:15]#[N:16].[K+].[CH3:18][Si:19](Cl)([CH3:21])[CH3:20]>[I-].[Zn+2].[I-].C(#N)C>[CH3:14][O:13][C:9]1[CH:8]=[C:5]([CH:6]([O:7][Si:19]([CH3:21])([CH3:20])[CH3:18])[C:15]#[N:16])[CH:4]=[C:3]([O:2][CH3:1])[C:10]=1[O:11][CH3:12]

Participants

6

Reactant 3

HCID 6397ChlorotrimethylsilaneHCID 68583,4,5-TrimethoxybenzaldehydeHCID 9032Potassium Cyanide

Product 1

HCID 15667547HCID 15667547, compound

Reagents, catalysts & solvents 2

HCID 9883512zinc(II)iodideCatalystHCID 6342AcetonitrileSolvent

Procedure

3,4,5-Trimethoxybenzaldehyde, acetonitrile, potassium cyanide, zinc (II) iodide and trimethylsilyl chloride are treated in the same manners as in the above procedure (1-a) to give (3,4,5-trimethoxyphenyl)(trimethylsilyloxy)acetonitrile as oily product.

Sources & evidence

ORD record
ord-5d37ea5ab4d84c6d8c6b2de3315d69eb
Source dataset
uspto-grants-1991_03
Patent number
US05003087

Reaction notes

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