(1,4-Dibenzyl-1,4-diazepan-6-yl)methanol → (1,4-Diazepan-6-yl)methanol

Participants

Reaction Steps

2.26 g (7.3 mmol) of (1,4-dibenzyl-[1,4]-diazepan-6-yl)-methanol are dissolved in 150 ml of methanol and hydrogenated at room temperature and normal pressure in the presence of 0.5 g of 10% palladium on activated charcoal. [1,4]-Diazepan-6-yl-methanol is obtained in the form of a light yellow oil by filtration and concentration of the filtrate.

Provenance & Evidence