HuagongsheHuagongshe Chemistry Print Report · For research reference only
(3aR*,10aS*)-9-(3-Nitrobenzyl)-2,3,3a,4,9,10a-hexahydrobenzo[b]cyclopenta[e][1,4]diazepin-10(1H)-one → (3aR*,10aS*)-9-(3-Aminobenzyl)-2,3,3a,4,9,10a-hexahydrobenzo[b]cyclopenta[e][1,4]diazepin-10(1H)-one
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | (3aR*,10aS*)-9-(3-Nitrobenzyl)-2,3,3a,4,9,10a-hexahydrobenzo[b]cyclopenta[e][1,4]diazepin-10(1H)-one | HCID 54235912 | — |
| Solvent | Diethyl Ether | HCID 3283 | — |
| Product | (3aR*,10aS*)-9-(3-Aminobenzyl)-2,3,3a,4,9,10a-hexahydrobenzo[b]cyclopenta[e][1,4]diazepin-10(1H)-one | HCID 54512889 | 84% |
Reaction Steps
Using (3aR*,10aS*)-9-(3-nitrobenzyl)-2,3,3a,4,9,10a-hexahydrobenzo[b]cyclopenta[e][1,4]diazepin-10(1H)-one, the title compound was synthesized in otherwise the same manner as Reference Example 7. Yield 84%, m.p. 176°-178° C. (diethyl ether).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05866567 |
| Source dataset | uspto-grants-1999_02 |
| ORD ID | ord-9e4cf158a3bb4baabb76971efc01caa0 |
| Source note | uspto-grants-1999_02 |