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HRID36161

反应详情

EQUATION

反应方程式

HRID 36161 的结构方程式

REACTANTS

反应物

2
结构：CCOC(=O)CC(=O)c1ccccc1
HCID7170

Ethyl benzoylacetate

C11H12O3

结构：COc1ccc2nc(N)sc2c1
HCID15630

6-Methoxy-2-benzothiazolamine

C8H8N2OS

PRODUCTS

生成物

1
结构：COc1ccc2nc(NC(=O)CC(=O)c3ccccc3)sc2c1
HCID19975336

未命名化合物

AUXILIARIES

试剂、催化剂与溶剂

1
结构：CC(C)=O
溶剂HCID180

Acetone

C3H6O

PROCEDURE

实验过程

Ethyl benzoyl acetate (9.5 ml) and 2-amino-6-methoxy benzothiazole (9.01 g) are heated to 140° under house vacuum for 2 hours. After cooling, the residue is taken up in acetone and filtered. The precipitate is dissolved in hot DMF to give an amide, N-(6-methoxybenzothiazol -2-yl)-3-oxo-3-phenylpropanamide (II).

WORKUP

后处理

  1. temperatureAfter cooling
  2. filtrationfiltered
  3. dissolutionThe precipitate is dissolved in hot DMF