Butyric anhydride → HCID 53804784, compound

HRID 361704Notes

Reaction equation

[C:1]([NH:4][C:5]1[CH:10]=[C:9]([Cl:11])[C:8]([OH:12])=[C:7]([Cl:13])[CH:6]=1)(=[O:3])[CH3:2].[C:14](OC(=O)CCC)(=O)[CH2:15]CC>>[C:1]([NH:4][C:5]1[CH:6]=[C:7]([Cl:13])[C:8]([OH:12])=[C:9]([Cl:11])[CH:10]=1)(=[O:3])[CH2:2][CH2:14][CH3:15]

Participants

Reactant 2

HCID 7798Butyric anhydride

HCID 100821803',5'-Dichloro-4'-hydroxyacetanilide

Product 1

HCID 53804784HCID 53804784, compound

Procedure

Using the method described above for the preparation of 4-acetamido-2,6-dichlorophenol (but using butyric anhydride in place of acetic anhydride) there was obtained 4-butyramido-2,-6-dichlorophenol (used as starting material in Example 51) as a solid, m.p. 146°-147°; NMR([CD3 ]2SO): 0.9(3H,t), 1.58(2H,m), 2.25(2H,t), 7.62(2H,s), 9.75(1H,br s) and 9.85(1H,s); m/z 248(M+H).

Sources & evidence

ORD record: ord-922aaa30586d4c26867d99a9f7e9bafe
Source dataset: uspto-grants-1999_02
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US05866611

Reaction notes

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