Acetic Acid → 42823-72-3

HRID 361746Notes

Reaction equation

HRID 361746 reaction equation
[ClH:1].[C:2]([C:5]1[CH:13]=[CH:12][C:8]([C:9](N)=[O:10])=[CH:7][CH:6]=1)(=[NH:4])[NH2:3].C(O)(=[O:16])C>Cl>[ClH:1].[C:2]([C:5]1[CH:13]=[CH:12][C:8]([C:9]([OH:16])=[O:10])=[CH:7][CH:6]=1)(=[NH:4])[NH2:3]

Participants

4

Reactant 2

HCID 176Acetic AcidHCID 27242934-Amidinobenzamide Hydrochloride

Product 1

HCID 4489083042823-72-3

Reagents, catalysts & solvents 1

HCID 313Hydrochloric AcidSolvent

Conditions

Temperature
110 °C

Procedure

4-Amidinobenzamide hydrochloride (10 g) was dissolved in a mixed solution of 6N HCl (300 ml) and acetic acid (50 ml) and the solution was refluxed at 110° C. for 6 hours. The reaction solution was cooled with ice and the resulting precipitate was filtered to yield a crystal of 4-amidinobenzoic acid hydrochloride (10.4 g).

Workup

  1. temperatureThe reaction solution was cooled with ice
  2. filtrationthe resulting precipitate was filtered

Sources & evidence

ORD record
ord-0b69150ec8aa466e8b25c7d11efbba19
Source dataset
uspto-grants-1999_02
Patent number
US05866592

Reaction notes

Loading…