HuagongsheHuagongshe Chemistry Print Report · For research reference only
Pyrrole-2-Carboxylic Acid → HCID 54413669, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Pyrrole-2-Carboxylic Acid | HCID 12473 | — |
| Reactant | 1,1'-Carbonyldiimidazole | HCID 68263 | — |
| Reactant | 1-Benzyl-4-[N-ethyl-N-(3-(2-methyl-1-propenyl)-2-pyridinyl)amino]piperidine | HCID 10665494 | — |
| Catalyst | Palladium hydroxide | HCID 9942167 | — |
| Product | HCID 54413669 | HCID 54413669 | — |
Reaction Steps
Following the general procedure of EXAMPLE 20 and making non-critical variations but starting with 1-benzyl-4-[N-ethyl-N-(3-(1-propenyl)-2-pyridinyl)amino]piperidine (XXII, EXAMPLE 19, 0.40 g, 1.20 mmol), Pearlman's catalyst (0.1 g), CDI (0.39 g, 2.4 mmol), and pyrrole-2-carboxylic acid (0.27 g, 2.4 mmol), the title compound is obtained, mp 115°-116°.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05866589 |
| Source dataset | uspto-grants-1999_02 |
| ORD ID | ord-4a17855b89b64ca3a04e7395071e64f8 |
| Source note | uspto-grants-1999_02 |