反应详情

Following the general procedure of EXAMPLE 20 and making non-critical variations but starting with 1-benzyl-4-[N-ethyl-N-(3-(1-propenyl)-2-pyridinyl)amino]piperidine (XXII, EXAMPLE 19, 0.40 g, 1.20 mmol), Pearlman's catalyst (0.1 g), CDI (0.39 g, 2.4 mmol), and pyrrole-2-carboxylic acid (0.27 g, 2.4 mmol), the title compound is obtained, mp 115°-116°.