HuagongsheHuagongshe Chemistry Print Report · For research reference only
Pyrrole-2-Carboxylic Acid → HCID 15392051, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Pyrrole-2-Carboxylic Acid | HCID 12473 | — |
| Reactant | 1,1'-Carbonyldiimidazole | HCID 68263 | — |
| Reactant | 1-Benzyl-4-[N-ethyl-N-(3-(2-methyl-1-propenyl)-2-pyridinyl)amino]piperidine | HCID 10665494 | — |
| Catalyst | Palladium hydroxide | HCID 9942167 | — |
| Product | HCID 15392051 | HCID 15392051 | — |
Reaction Steps
Following the general procedure of EXAMPLE 20 and making non-critical variations but starting with 1-benzyl-4-(N-methyl-N-(3-(1-propenyl)-2-pyridinyl)amino)piperidine (XXII, EXAMPLE 14, 0.46 g, mmol), Pearlman's catalyst (0.1 g), CDI (0.46 g, 2.85 mmol) and pyrrole-2-carboxylic acid (0.32 g, 2.85 mmol), the title compound is obtained, mp 88°-90°.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05866589 |
| Source dataset | uspto-grants-1999_02 |
| ORD ID | ord-91fef5ba82934ec489920cc022a1722d |
| Source note | uspto-grants-1999_02 |