反应详情

Following the general procedure of EXAMPLE 70, and making non-critical variations but substituting 1-benzyl-4-(1-methylethylamino)piperidine (EXAMPLE 99) for 1-benzyl-4-(methylamino)piperidine and 2-chloro-3-nitropyridine for 2-bromo-3-ethoxypyridine and using a reaction time of 2 hrs, the title compound is obtained, NMR (CDCl3) 8.24, 7.90, 7.31-7.23, 6.62, 3.61, 3.49, 2.97, 2.27, 1.96, 1.77 and 1.39δ.

1. customa reaction time of 2 hrs