HuagongsheHuagongshe Chemistry Print Report · For research reference only
Acetaldehyde → 1-benzyl-4-[N-ethyl-N-(3-(isopropylamino)-2-pyridinyl)amino]piperidine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Acetaldehyde | HCID 177 | — |
| Reactant | Acetone | HCID 180 | — |
| Reactant | 1-Benzyl-4-[N-propyl-N-(3-amino-2-pyridinyl)amino]piperidine | HCID 10568019 | — |
| Product | 1-benzyl-4-[N-ethyl-N-(3-(isopropylamino)-2-pyridinyl)amino]piperidine | HCID 10689357 | — |
Reaction Steps
Following the general procedure of EXAMPLE 115 and making non-critical variations but substituting 1-benzyl-4-[N-ethyl-N-(3-amino-2-pyridinyl)amino]piperidine (PREPARATION 4) for 1-benzyl-4-[N-propyl-N-(3-amino-2-pyridinyl)amino]piperidine and acetone for acetaldehyde, the title compound is obtained, NMR (CDCl3) 7.71, 7.30, 7.25, 6.80, 4.72, 3.55, 3.50, 3.11, 3.00, 2.88, 2.00, 1.74, 1.66, 1.20 and 0.86δ.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05866589 |
| Source dataset | uspto-grants-1999_02 |
| ORD ID | ord-5a79f2b68c794c5fa3ce13273714cb61 |
| Source note | uspto-grants-1999_02 |