HuagongsheHuagongshe Chemistry Print Report · For research reference only
HCID 67576838, compound → HCID 54501805, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | HCID 67576838 | HCID 67576838 | — |
| Reactant | HCID 178418361 | HCID 178418361 | — |
| Catalyst | Platinum hydroxide (Pt(OH)2) | HCID 9859412 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | HCID 54501805 | HCID 54501805 | — |
Reaction Steps
1-Benzyl-4-[N-ethyl-N-(3-isopropyl-2-pyridinyl)amino]methylpiperidine (EXAMPLE 178, 1.82 g, 4.97 mmol) and platinum hydroxide on carbon (675 mg) in 30 ml ethanol is hydrogenated at 40 p.s.i. hydrogen for 48 hrs. Filtration and evaporation of the solvent gives the title compound, NMR (300 MHz, CD3OD) 7.56, 6.97, 3.60, 2.94, 2.44, 1.69, 1.48, 1.20, 1.10 and 0.99δ.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05866589 |
| Source dataset | uspto-grants-1999_02 |
| ORD ID | ord-53928660f8e0429e83f4df8b8adbe177 |
| Source note | uspto-grants-1999_02 |