HuagongsheHuagongshe Chemistry Print Report · For research reference only
Methyl 4-benzyloxy-alpha-azidocinnamate → methyl 6-(benzyloxy)-1H-indole-2-carboxylate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Methyl 4-benzyloxy-alpha-azidocinnamate | HCID 54271879 | — |
| Solvent | Toluene | HCID 1140 | — |
| Product | methyl 6-(benzyloxy)-1H-indole-2-carboxylate | HCID 4715068 | — |
Reaction Steps
Methyl 4-benzyloxy-α-azidocinnamate (EXAMPLE 246, 5.8 g) is dissolved in 376 ml of toluene and the reaction is heated to reflux for 1 hr. Then the reaction is cooled, concentrated under reduced pressure and the solids are recrystallized from ethyl acetate/hexane to provide the title compound.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05866589 |
| Source dataset | uspto-grants-1999_02 |
| ORD ID | ord-4b7ec0b24fde4a0f889878d01e358f80 |
| Source note | uspto-grants-1999_02 |